The Incredible Hulk #6 - November 1977
First appearance of Poragon - "later becomes" Her, Kismet & Ayesha...
Dr Strange appearance as well.
If you are tyring to figure out the logic in this just think "Comics" but seriously Poragon was created the same way Adam Warlock was, in a Cocoon.
This will be a key issue more than it than it already is due to the Guardians of the Galaxy 3 to be released soon. Kismet/Ayesha is the Gold queen in the second Guardians film and at the end talks about Adam Warlock.
The Comic Condition:
The comic is in okay condition a staple has pushed through on the bottom (see photo) and it has wear on the spine and edges with slight tears and marks. (see photos)
Keep in mind this comic is 43 years old.
I would grade it a 5 out of 10